VWD affect males and females equally. The majority of the cases are “inherited”, passed from parents to children through their genes. Some cases are due to “spontaneous mutations” caused by a change in the gene that carries the instructions to produce the VW factor.
Type 1 and type 2:
- Usually inherited.
- One of the parents has the mutated gene and has a 50% chance of passing it to the child.
- Parent may not know they carry the mutated gene because their symptoms may be very mild or don’t have symptoms at all.
- Type 3 is always inherited.
- Both parents pass the gene to the child.