Page 2 - HFA Dateline 2022 Special Edition

T:8.5"
S:7.5"

When it comes to your hemophilia A treatment B:8.75"
Move beyond the threshold a

Esperoct can give you high factor levels for longer. b
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Extend half-life beyond the standard 22-hour average half-life in adults c

FOR ADULTS AND ADOLESCENTS
Switching made easy High factor levels Flexible on the go
with a standard 50 IU/kg dose every 4 days At or above 3% The ONLY extended half-life
-50% fewer infusions if you previously infused for 100% of the time d,e product that can be stored
every other day At or above 5% up to 104°F g
Please see Brief Summary for
-40% fewer infusions if you previously infused 3x a week for 90% of the time d,f complete storage instructions.
Safety Proven across 5 studies, the largest and longest EHL clinical trial program

a Of 1% trough factor levels for standard half-life (SHL) products in adults and adolescents.
b Compared with SHL products.
c Data shown are from 42 adults who received a pharmacokinetic (PK) assessment around the first Esperoct 50 IU/kg dose.
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d Trough level goal is 1% for prophylaxis.
e Data shown are from a study where 175 previously treated adolescents and adults received routine prophylaxis with Esperoct 50 IU/kg every 4 days.
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Pre-dose factor activity (trough) levels were evaluated at follow-up visits. Mean trough levels for adolescents (12-<18 years) were 2.7 IU/dL.
f Steady-state FVIII activity levels were estimated in 143 adults and adolescents using pharmacokinetic modeling.
g For up to 3 months. S:9.875" T:11" B:11.25"
What is Esperoct ? What should I tell my healthcare provider before
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Esperoct [antihemophilic factor (recombinant), glycopegylated- using Esperoct ?
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®
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exei] is an injectable medicine to treat and prevent or reduce • Before taking Esperoct , you should tell your healthcare
the number of bleeding episodes in people with hemophilia A. provider if you have or have had any medical conditions, take
Your healthcare provider may give you Esperoct when you any medicines (including non-prescription medicines and
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have surgery dietary supplements), are nursing, pregnant or planning to
• Esperoct is not used to treat von Willebrand Disease become pregnant, or have been told that you have inhibitors
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to factor VIII
IMPORTANT SAFETY INFORMATION • Your body can make antibodies called “inhibitors” against
Who should not use Esperoct ? Esperoct , which may stop Esperoct from working properly.
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• You should not use Esperoct if you are allergic to factor VIII Call your healthcare provider right away if your
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or any of the other ingredients of Esperoct or if you are bleeding does not stop after taking Esperoct ®
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allergic to hamster proteins What are the possible side effects of Esperoct ?
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What is the most important information I need to know • Common side effects of Esperoct include rash or itching,
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about Esperoct ? and swelling, pain, rash or redness at the location of infusion
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• Do not attempt to do an infusion yourself unless you
have been taught how by your healthcare provider or Please see Brief Summary of Prescribing Information
hemophilia treatment center on the following page.
• Call your healthcare provider right away or get
emergency treatment right away if you get any signs of
an allergic reaction, such as: hives, chest tightness, wheezing, Discover more at Esperoct.com.
dizziness, dif culty breathing, and/or swelling of the face

Novo Nordisk Inc., 800 Scudders Mill Road, Plainsboro,
New Jersey 08536 U.S.A.
®
Esperoct is a registered trademark of Novo Nordisk Health Care AG.
Novo Nordisk is a registered trademark of Novo Nordisk A/S.
© 2020 Novo Nordisk Printed in the USA. US20ESP00014 February 2020

PREPARED BY
11648998 N8 GP PATIENT JOURNAL AD RESIZE M2FR

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