If you have hemophilia A (also called classic hemophilia), you are missing or have a deficiency (lower level) of clotting factor VIII (FVIII). This means your blood cannot successfully form a clot. Hemophilia A is hereditary. Because it is an X-chromosome-linked condition, males are more typically affected and therefore more frequently diagnosed. Hemophilia A affects one in 5,000 male births in the U.S., and approximately 400 babies are born with hemophilia each year. Over 1.1 million people worldwide are living with hemophilia, and about 30,000 are living with it in the United States. All races and economic groups are affected equally.
Most people with hemophilia A who have access to appropriate medical treatment have a normal life expectancy and are able to lead a fairly normal life.
A female carrier of hemophilia who experiences bleeding symptoms is called a symptomatic carrier if her level is over 50%, and she has bleeding symptoms. Carrier females who have between 5% and 50% have mild hemophilia. Hemophilia A severity is the same for women as it is for men. Women with hemophilia and symptomatic carriers have the same symptoms as anyone with hemophilia. Some carriers have completely normal levels of FVIII and do not exhibit any signs of bleeding.
If you have hemophilia A, you should have regular checkups with a hematologist or visit a Hemophilia Treatment Center annually. If you or someone in your family experiences hemophilia A symptoms, and you have not yet been diagnosed, you should contact your medical provider for a referral to a hematologist or HTC for testing and diagnosis.