If you have inherited VWD, how you inherited it will depend on your VWD type. If you have a spontaneous mutation, your descendants will inherit VWD according to your type. In addition to the types listed below, one parent can have a genetic mutation, and the child can have a mutation as well, causing VWD.
VWD type 1, VWD type 2 (all subtypes except 2n), and pseudo-VWD are all autosomal dominant. This means that even if only one parent has the mutated VWF gene, there is a chance of their children having VWD.
VWD type 3 and VWD type 2n are autosomal recessive. This means that both parents must have the defective VWF gene to create the possibility that their child will have VWD.
